<!doctype html><html lang=en-us><head><meta charset=utf-8><meta name=viewport content="width=device-width,initial-scale=1"><meta http-equiv=x-ua-compatible content="IE=edge"><meta name=generator content="Wowchemy 5.1.0 for Hugo"><meta name=author content="Célia Souque"><meta name=description content="Lorem ipsum dolor sit amet, consectetur adipiscing elit. Duis posuere tellus ac convallis placerat. Proin tincidunt magna sed ex sollicitudin condimentum."><link rel=alternate hreflang=en-us href=https://celia-souque.com/elifesciences.org/articles/62474><link rel=preconnect href=https://fonts.gstatic.com crossorigin><meta name=theme-color content="rgb(0, 102, 153)"><link rel=stylesheet href=https://cdnjs.cloudflare.com/ajax/libs/academicons/1.9.0/css/academicons.min.css integrity="sha512-W4yqoT1+8NLkinBLBZko+dFB2ZbHsYLDdr50VElllRcNt2Q4/GSs6u71UHKxB7S6JEMCp5Ve4xjh3eGQl/HRvg==" crossorigin=anonymous><link rel=stylesheet href=https://cdnjs.cloudflare.com/ajax/libs/font-awesome/5.14.0/css/all.min.css integrity="sha256-FMvZuGapsJLjouA6k7Eo2lusoAX9i0ShlWFG6qt7SLc=" crossorigin=anonymous><link rel=stylesheet href=https://cdnjs.cloudflare.com/ajax/libs/highlight.js/10.2.0/styles/github.min.css crossorigin=anonymous title=hl-light media=print onload="this.media='all'"><link rel=stylesheet href=https://cdnjs.cloudflare.com/ajax/libs/highlight.js/10.2.0/styles/dracula.min.css crossorigin=anonymous title=hl-dark media=print onload="this.media='all'" disabled><link rel=preload as=style href="https://fonts.googleapis.com/css2?family=Cutive+Mono&family=Lora:wght@400;700&family=Roboto:wght@400;700&display=swap&display=swap"><link rel=stylesheet href="https://fonts.googleapis.com/css2?family=Cutive+Mono&family=Lora:wght@400;700&family=Roboto:wght@400;700&display=swap&display=swap" media=print onload="this.media='all'"><link rel=stylesheet href=/css/wowchemy.a92896ec063a29fc11fa6a5f1dfff024.css><link rel=manifest href=/index.webmanifest><link rel=icon type=image/png href=/media/icon_hu0b7a4cb9992c9ac0e91bd28ffd38dd00_9727_32x32_fill_lanczos_center_2.png><link rel=apple-touch-icon type=image/png href=/media/icon_hu0b7a4cb9992c9ac0e91bd28ffd38dd00_9727_180x180_fill_lanczos_center_2.png><link rel=canonical href=https://celia-souque.com/elifesciences.org/articles/62474><meta property="twitter:card" content="summary"><meta property="og:site_name" content="Célia Souque"><meta property="og:url" content="https://celia-souque.com/elifesciences.org/articles/62474"><meta property="og:title" content="Integron activity accelerates the evolution of antibiotic resistance | Célia Souque"><meta property="og:description" content="Lorem ipsum dolor sit amet, consectetur adipiscing elit. Duis posuere tellus ac convallis placerat. Proin tincidunt magna sed ex sollicitudin condimentum."><meta property="og:image" content="https://celia-souque.com/media/icon_hu0b7a4cb9992c9ac0e91bd28ffd38dd00_9727_512x512_fill_lanczos_center_2.png"><meta property="twitter:image" content="https://celia-souque.com/media/icon_hu0b7a4cb9992c9ac0e91bd28ffd38dd00_9727_512x512_fill_lanczos_center_2.png"><meta property="og:locale" content="en-us"><meta property="article:published_time" content="2017-01-01T00:00:00+00:00"><meta property="article:modified_time" content="2021-03-25T16:36:15+00:00"><script type=application/ld+json>{"@context":"https://schema.org","@type":"Article","mainEntityOfPage":{"@type":"WebPage","@id":"https://celia-souque.com/elifesciences.org/articles/62474"},"headline":"Integron activity accelerates the evolution of antibiotic resistance","datePublished":"2017-01-01T00:00:00Z","dateModified":"2021-03-25T16:36:15Z","author":{"@type":"Person","name":"Célia Souque"},"publisher":{"@type":"Organization","name":"Célia Souque","logo":{"@type":"ImageObject","url":"https://celia-souque.com/media/icon_hu0b7a4cb9992c9ac0e91bd28ffd38dd00_9727_192x192_fill_lanczos_center_2.png"}},"description":"Lorem ipsum dolor sit amet, consectetur adipiscing elit. Duis posuere tellus ac convallis placerat. Proin tincidunt magna sed ex sollicitudin condimentum."}</script><title>Integron activity accelerates the evolution of antibiotic resistance | Célia Souque</title></head><body id=top data-spy=scroll data-offset=70 data-target=#TableOfContents class=page-wrapper data-wc-page-id=74320c7581d6941258c2324311d4eeeb><script src=/js/wowchemy-init.min.9dad2fecac7f370e439d06c4a1b59e05.js></script><aside class=search-modal id=search><div class=container><section class=search-header><div class="row no-gutters justify-content-between mb-3"><div class=col-6><h1>Search</h1></div><div class="col-6 col-search-close"><a class=js-search href=# aria-label=Close><i class="fas fa-times-circle text-muted" aria-hidden=true></i></a></div></div><div id=search-box><input name=q id=search-query placeholder=Search... autocapitalize=off autocomplete=off autocorrect=off spellcheck=false type=search class=form-control aria-label=Search...></div></section><section class=section-search-results><div id=search-hits></div></section></div></aside><div class=page-header><nav class="navbar navbar-expand-lg navbar-light compensate-for-scrollbar" id=navbar-main><div class=container-xl><div class="d-none d-lg-inline-flex"><a class=navbar-brand href=/>Célia Souque</a></div><button type=button class=navbar-toggler data-toggle=collapse data-target=#navbar-content aria-controls=navbar aria-expanded=false aria-label="Toggle navigation">
<span><i class="fas fa-bars"></i></span></button><div class="navbar-brand-mobile-wrapper d-inline-flex d-lg-none"><a class=navbar-brand href=/>Célia Souque</a></div><div class="navbar-collapse main-menu-item collapse justify-content-start" id=navbar-content><ul class="navbar-nav d-md-inline-flex"><li class=nav-item><a class=nav-link href=/#about><span><font size=+1>Home</font></span></a></li><li class=nav-item><a class=nav-link href=/publications><span><font size=+1>Publications</font></span></a></li><li class=nav-item><a class=nav-link href=/celiasouquecv2021.pdf><span><font size=+1>CV</font></span></a></li><li class=nav-item><a class=nav-link href=/contact><span><font size=+1>Contact</font></span></a></li></ul></div><ul class="nav-icons navbar-nav flex-row ml-auto d-flex pl-md-2"></ul></div></nav></div><div class=page-body><div class=pub><div class="article-container pt-3"><h1>Integron activity accelerates the evolution of antibiotic resistance</h1><div class=article-metadata><div><span><a href=/authors/admin/>Célia Souque</a></span>, <span><a href=/authors/jose-antonio-escudero/>José Antonio Escudero</a></span>, <span><a href=/authors/craig-maclean/>Craig MacLean</a></span></div><span class=article-date>February 2021</span></div><div class="btn-links mb-3"><a class="btn btn-outline-primary btn-page-header" href=https://doi.org/10.7554/eLife.62474 target=_blank rel=noopener>DOI</a></div></div><div class=article-container><h3>Abstract</h3><p class=pub-abstract>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Duis posuere tellus ac convallis placerat. Proin tincidunt magna sed ex sollicitudin condimentum. Sed ac faucibus dolor, scelerisque sollicitudin nisi. Cras purus urna, suscipit quis sapien eu, pulvinar tempor diam. Quisque risus orci, mollis id ante sit amet, gravida egestas nisl. Sed ac tempus magna. Proin in dui enim. Donec condimentum, sem id dapibus fringilla, tellus enim condimentum arcu, nec volutpat est felis vel metus. Vestibulum sit amet erat at nulla eleifend gravida.</p><div class=row><div class=col-md-1></div><div class=col-md-10><div class=row><div class="col-12 col-md-3 pub-row-heading">Type</div><div class="col-12 col-md-9"><a href=/publication/#2>Journal article</a></div></div></div><div class=col-md-1></div></div><div class="d-md-none space-below"></div><div class=row><div class=col-md-1></div><div class=col-md-10><div class=row><div class="col-12 col-md-3 pub-row-heading">Publication</div><div class="col-12 col-md-9"><em>eLife</em></div></div></div><div class=col-md-1></div></div><div class="d-md-none space-below"></div><div class=space-below></div><div class=article-style></div><div class=article-tags><a class="badge badge-light" href=/tag/source-themes/>Source Themes</a></div><div class=share-box aria-hidden=true><ul class=share><li><a href="https://twitter.com/intent/tweet?url=https://celia-souque.com/elifesciences.org/articles/62474&text=Integron%20activity%20accelerates%20the%20evolution%20of%20antibiotic%20resistance" target=_blank rel=noopener class=share-btn-twitter><i class="fab fa-twitter"></i></a></li><li><a href="https://www.facebook.com/sharer.php?u=https://celia-souque.com/elifesciences.org/articles/62474&t=Integron%20activity%20accelerates%20the%20evolution%20of%20antibiotic%20resistance" target=_blank rel=noopener class=share-btn-facebook><i class="fab fa-facebook"></i></a></li><li><a href="mailto:?subject=Integron%20activity%20accelerates%20the%20evolution%20of%20antibiotic%20resistance&body=https://celia-souque.com/elifesciences.org/articles/62474" target=_blank rel=noopener class=share-btn-email><i class="fas fa-envelope"></i></a></li><li><a href="https://www.linkedin.com/shareArticle?url=https://celia-souque.com/elifesciences.org/articles/62474&title=Integron%20activity%20accelerates%20the%20evolution%20of%20antibiotic%20resistance" target=_blank rel=noopener class=share-btn-linkedin><i class="fab fa-linkedin-in"></i></a></li><li><a href="whatsapp://send?text=Integron%20activity%20accelerates%20the%20evolution%20of%20antibiotic%20resistance%20https://celia-souque.com/elifesciences.org/articles/62474" target=_blank rel=noopener class=share-btn-whatsapp><i class="fab fa-whatsapp"></i></a></li><li><a href="https://service.weibo.com/share/share.php?url=https://celia-souque.com/elifesciences.org/articles/62474&title=Integron%20activity%20accelerates%20the%20evolution%20of%20antibiotic%20resistance" target=_blank rel=noopener class=share-btn-weibo><i class="fab fa-weibo"></i></a></li></ul></div><div class="media author-card content-widget-hr"><a href=https://celia-souque.com><img class="avatar mr-3 avatar-circle" src=/authors/admin/avatar_hu0fc85ef21a8d6a0e6fcbc041bdbc239a_254726_270x270_fill_q75_lanczos_center.jpg alt="Célia Souque"></a><div class=media-body><h5 class=card-title><a href=https://celia-souque.com>Célia Souque</a></h5><h6 class=card-subtitle>Postdoctoral Research Fellow</h6><ul class=network-icon aria-hidden=true><li><a href=/contact><i class="fas fa-envelope"></i></a></li><li><a href=https://twitter.com/Celia_Sqe target=_blank rel=noopener><i class="fab fa-twitter"></i></a></li><li><a href="https://scholar.google.com/citations?user=kHdzeBsAAAAJ&hl=en" target=_blank rel=noopener><i class="fas fa-graduation-cap"></i></a></li><li><a href=https://www.linkedin.com/in/c%C3%A9lia-souque-9b49a380/ target=_blank rel=noopener><i class="fab fa-linkedin"></i></a></li></ul></div></div><div class="article-widget content-widget-hr"><h3>Related</h3><ul><li><a href=/publication/thesis/>An example journal article</a></li><li><a href=/publication/test/>An example journal article</a></li></ul></div></div></div></div><div class=page-footer><div class=container><footer class=site-footer><p class=powered-by>@2021 - Célia Souque</p><p class=powered-by>Published with <a href="https://wowchemy.com/?utm_campaign=poweredby" target=_blank rel=noopener>Wowchemy</a> — the free, <a href=https://github.com/wowchemy/wowchemy-hugo-modules target=_blank rel=noopener>open source</a> website builder that empowers creators.</p></footer></div></div><div id=modal class="modal fade" role=dialog><div class=modal-dialog><div class=modal-content><div class=modal-header><h5 class=modal-title>Cite</h5><button type=button class=close data-dismiss=modal aria-label=Close>
<span aria-hidden=true>×</span></button></div><div class=modal-body><pre><code class="tex hljs"></code></pre></div><div class=modal-footer><a class="btn btn-outline-primary my-1 js-copy-cite" href=# target=_blank><i class="fas fa-copy"></i>Copy</a>
<a class="btn btn-outline-primary my-1 js-download-cite" href=# target=_blank><i class="fas fa-download"></i>Download</a><div id=modal-error></div></div></div></div></div><script src=https://cdnjs.cloudflare.com/ajax/libs/jquery/3.5.1/jquery.min.js integrity="sha256-9/aliU8dGd2tb6OSsuzixeV4y/faTqgFtohetphbbj0=" crossorigin=anonymous></script><script src=https://cdnjs.cloudflare.com/ajax/libs/instant.page/5.1.0/instantpage.min.js integrity="sha512-1+qUtKoh9XZW7j+6LhRMAyOrgSQKenQ4mluTR+cvxXjP1Z54RxZuzstR/H9kgPXQsVB8IW7DMDFUJpzLjvhGSQ==" crossorigin=anonymous></script><script src=https://cdnjs.cloudflare.com/ajax/libs/jquery.imagesloaded/4.1.4/imagesloaded.pkgd.min.js integrity="sha256-lqvxZrPLtfffUl2G/e7szqSvPBILGbwmsGE1MKlOi0Q=" crossorigin=anonymous></script><script src=https://cdnjs.cloudflare.com/ajax/libs/jquery.isotope/3.0.6/isotope.pkgd.min.js integrity="sha256-CBrpuqrMhXwcLLUd5tvQ4euBHCdh7wGlDfNz8vbu/iI=" crossorigin=anonymous></script><script src=https://cdnjs.cloudflare.com/ajax/libs/highlight.js/10.2.0/highlight.min.js integrity="sha512-TDKKr+IvoqZnPzc3l35hdjpHD0m+b2EC2SrLEgKDRWpxf2rFCxemkgvJ5kfU48ip+Y+m2XVKyOCD85ybtlZDmw==" crossorigin=anonymous></script><script src=https://cdnjs.cloudflare.com/ajax/libs/highlight.js/10.2.0/languages/r.min.js></script><script id=search-hit-fuse-template type=text/x-template>
<div class="search-hit" id="summary-{{key}}">
<div class="search-hit-content">
<div class="search-hit-name">
<a href="{{relpermalink}}">{{title}}</a>
<div class="article-metadata search-hit-type">{{type}}</div>
<p class="search-hit-description">{{snippet}}</p>
</div>
</div>
</div>
</script><script src=https://cdnjs.cloudflare.com/ajax/libs/fuse.js/3.2.1/fuse.min.js integrity="sha256-VzgmKYmhsGNNN4Ph1kMW+BjoYJM2jV5i4IlFoeZA9XI=" crossorigin=anonymous></script><script src=https://cdnjs.cloudflare.com/ajax/libs/mark.js/8.11.1/jquery.mark.min.js integrity="sha256-4HLtjeVgH0eIB3aZ9mLYF6E8oU5chNdjU6p6rrXpl9U=" crossorigin=anonymous></script><script src=/js/bootstrap.bundle.min.6aed84840afc03ab4d5750157f69c120.js></script><script src=/en/js/wowchemy.min.b61a8f62b6e5c0cd322c8158c5b5dfb6.js></script></body></html>